Below you can view all of the projects that Ohio Cancer Research has funded, starting with the most recent. Select an institution or cancer type from the relative drop downs below to view projects funded in those areas.
Total Funding
Ohio Cancer Research
OCR Funding:
Additional Funding Generated:
Cleveland Clinic
Lai (Linda) Chan, PhD
Years: 2024-2026
Grant Awarded: $80,000
Generated: TBD
Cancer Type:
Leukemia
Project:
Exploiting Pathway Incompatibility for Targeted Therapy in STAT5-Pathway Mutated B-Cell Leukemia
"Despite recent advancements in treatments, approximately 20% of patients with B-cell acute lymphoblastic leukemia experience a return of the disease within two years of initial treatments. Only about half of these patients survive when leukemia returns. Funding from OCR will allow us to explore innovative approaches to treat leukemia and prevent the development of drug resistance. Our research aims to minimize the likelihood of disease recurrence and improve clinical outcomes."
Funding provided by Kimball Midwest/The McCurdy Family
Cleveland State University
Kailash Gulshan, PhD
Years: 2024-2026
Grant Awarded: $80,000
Generated: TBD
Cancer Type:
Lung Cancer
Project:
Targeting Inflammasome Activity in Lung Cancer
"Lung cancer is the leading cause of cancer-related deaths worldwide, thus novel anti-lung cancer therapeutic approaches are urgently needed. Our research will open novel therapeutic and research avenues for targeting lung cancer. Support from OCR serves as a foundation for this innovative project, aiming to identify pathways that can be targeted to treat lung cancer."
Nationwide Children's Hospital
Prajwal Rajappa, MD, MS
Years: 2023-2025
Grant Awarded: $80,000
Generated: $2,821,704
Cancer Type:
Brain Cancer
Project:
IL-12 Secreting Genetically Modified Myeloid Cells and Immune Checkpoint Blockade to Prevent Glioma Malignant Progression
"Our funded project with OCR will focus on utilizing IL-12 secreting myeloid cells and immune checkpoint blockade for the activation of cytotoxic cells to kill glioma cells before they undergo malignant progression. Having the support of OCR is critical for our ability to develop these novel innate immunotherapies."
Funding provided by Kimball Midwest/The McCurdy Family
University of Toledo
Shi-He Liu, MD
Years: 2023-2025
Grant Awarded: $80,000
Generated: $2,490,190
Cancer Type:
Pancreatic Cancer
Project:
Engineering Exosome for Pancreatic Cancer Targeting Therapies
"Pancreatic cancer remains one of deadliest forms of cancer in the United States with a 5-year survival rate of less than 10 percent. The generous funding from Ohio Cancer Research will lay the groundwork for our research to receive federal funding and help to improve outcomes for pancreatic cancer patients."
Cleveland Clinic Foundation
Mihriban Karaayvaz, PhD
Years: 2023-2025
Grant Awarded: $80,000
Generated: TBD
Cancer Type:
Breast Cancer
Project:
Modulation of mechanosignaling in the prevention of BRCA1/2 mutant breast cancer
"Breast cancer is the most common cancer in females, affecting one in every eight women and accounting for the majority of cancer-related deaths in women worldwide. The generous funding from Ohio Cancer Research will pave the way for our research to receive federal funding and to improve breast cancer patient outcomes by developing novel prevention strategies."
The Ohio State University
Priya Dedhia, MD, PhD
Years: 2022-2024
Grant Awarded: $60,000
Generated: $2,059,126
Cancer Type:
Adrenal Gland Cancer
Project:
Intratumoral Hetergeneity in Adrencortical Carcinoma
"Sponsorship from Ohio Cancer Research will allow us to use the novel models of adrenocortical carcinoma developed in our lab to understand the mechanisms of disease progression. We can then use these findings to identify new targets to improve outcomes for patients with this devastating disease."
Funding provided by Kimball Midwest/The McCurdy Family
Cleveland Clinic Foundation
Liangqi Xie, PhD
Years: 2022-2024
Grant Awarded: $60,000
Generated: $1,449,000
Cancer Type:
Colon Cancer
Project:
Targeting BET Protein-Regulated MYC Extrachromosomal DNA in Colon Cancer
"The seed funding from Ohio Cancer Research is tremendous for a new investigator to test bold ideas. With this important support, I hope to light up cancer cells using advanced molecular imaging and discover new cancer vulnerabilities for effective cancer treatment."
The Ohio State University
Amanda Panfil, PhD
Years: 2021-2023
Grant Awarded: $60,000
Generated: $30,000
Cancer Type:
Leukemia/Lymphona - Adult
Project:
The Effects of m6A RNA Modifications on the Oncogenic Retrovirus HTLV-1
"Adult T-cell leukemia/lymphoma (ATL) is an aggressive and fatal T-cell malignancy caused by the retrovirus HTLV-1. These OCR funds will support research that allows us to better understand the disease process and unlock new approaches for the treatment of ATL."
Funding provided by Kimball Midwest/The McCurdy Family
Case Western Reserve University
Amar B Desai, PhD
Years: 2021-2023
Grant Awarded: $60,000
Generated: $201,250
Cancer Type:
Cancer Therapy
Project:
Identifying Novel Effectors of 15-PGDH Mediated Regeneration
"This award provides my lab the funds necessary to pursue novel approaches to better understand and treat blood disorders. Support from OCR gives us the freedom to think outside the box, which is essential to push science forward."
Wright State University
Michael G Kemp, PhD
Years: 2020-2022
Grant Awarded: $60,000
Generated: $1,078,245
Cancer Type:
Prevention & Treatment
Project:
Circadian Clock Modulating Drugs in Cancer Prevention and Treatment
"Funding from OCR will allow us to explore the exciting idea that the body’s circadian rhythm can be therapeutically modified to both prevent cancer development and improve the effectiveness of existing anti-cancer therapeutics."
Cincinnati Children's Hospital MC
Andrew Volk, PhD
Years: 2020-2022
Grant Awarded: $60,000
Generated: $1,441,500
Cancer Type:
Leukemia
Project:
The Role of Chromatin Assembly in Down Syndrome-related Acute Megakaryoblastic Leukemia
"Our hearts and our efforts go out to the families struggling with a leukemia diagnosis. This grant from OCR is the first major award for our independent research group, and we are incredibly grateful to the organization and its donors for their critical support while we are establishing our research program. We will use these funds to probe the molecular drivers of the leukemias that affect children with Down syndrome, and we hope that our research can improve the quality of care that they, and by extension all leukemia patients, receive as they battle this disease."
Funding provided by Kimball Midwest/The McCurdy Family
The Ohio State University
Emanuele Cocucci
Years: 2019-2021
Grant Awarded: $60,000
Generated: $2,600,000
Cancer Type:
Breast Cancer
Project:
Dissecting mechanisms of intercellular communication between breast cancer cells mediated by extracellular vesicles
Funding provided by Kimball Midwest/The McCurdy Family
University of Cincinnati
Atsuo Sasaki
Years: 2018-2019
Grant Awarded: $60,000
Generated: $1,806,457
Cancer Type:
Brain Cancer
Project:
Targeting the metabolic vulnerability of GTP-metabolism in IDH mutated glioma
University of Toledo
Saori Furuta, PhD
Years: 2017-2018
Grant Awarded: $60,000
Generated: $1,506,341
Cancer Type:
Breast Cancer
Project:
Role of nitric oxide in regulating the extracellular matrix in breast
University of Toledo
Dayanidhi Raman, PhD
Years: 2017-2018
Grant Awarded: $60,000
Generated: $2,833,372
Cancer Type:
Breast Cancer
Project:
Role of CXCR4-LASP-1 axis in modulating the activity of Argonaute2-TNRC6 in breast cancer cells
University of Toledo
Heather Conti, PhD
Years: 2016-2017
Grant Awarded: $60,000
Generated: $3,595,452
Cancer Type:
Radiotherapy
Project:
Proinflammatory cytokines IL-‐23 and IL-‐17 in radiotherapy induced oral mucositis
Case Western Reserve University
Vinay Varadan, PhD
Years: 2016-2017
Grant Awarded: $60,000
Generated: $1,523,378
Cancer Type:
Breast Cancer
Project:
lmmunosuppressive mechanisms and response prediction in HER2+ early breast cancer
The Ohio State University
Anne Strohecker, PhD
Years: 2015-2016
Grant Awarded: $60,000
Generated: $907,700
Cancer Type:
Lung Cancer
Project:
Regulation of Autophagy by the small GTPase Rab20
The Ohio State University
Jennifer Leight, PhD
Years: 2015-2016
Grant Awarded: $60,000
Generated: $240,000
Cancer Type:
Cancer Therapy
Project:
Impact of the tumor microenvironment on matrix metalloproteinase activity
Case Western Reserve University
Huiping Liu, MD, PhD
Years: 2015-2016
Grant Awarded: $60,000
Generated: $5,138,504
Cancer Type:
Breast Cancer
Project:
Targeting IL-11 in breast tumor initating cell-mediated metastasis
University of Toledo
Rafael Garcia-Mata, PhD
Years: 2013-2014
Grant Awarded: $60,000
Generated: $2,525,265
Cancer Type:
Breast Cancer
Project:
Molecular Mechanisms of Invadopodia Formation in Breast Cancer Cells
Case Western Reserve University
Efstathios Karathanasis, PhD
Years: 2013
Grant Awarded: $60,000
Generated: $7,618,276
Cancer Type:
Chemotherapy
Project:
Treatment of cancer metastasis using a multicomponent nanoparticle
Cincinnati Children's Hospital MC
Saulius Sumanas, PhD
Years: 2013
Grant Awarded: $60,000
Generated: $4,381,672
Cancer Type:
Tumor Studies
Project:
Inhibition of Etv2 function as a novel strateg to prevent tumor-induced
Cleveland Clinic Foundation
Matthew K Summers, PhD
Years: 2012-2013
Grant Awarded: $60,000
Generated: $2,388,926
Cancer Type:
Breast Cancer
Project:
The role of p31comet in breast cancer progression and therapy
Cleveland Clinic Foundation
Justin Lathia, PhD
Years: 2012-2013
Grant Awarded: $60,000
Generated: $24,200,862
Cancer Type:
Brain Cancer
Project:
Targeting CXCR7 mediated vascular interactions in Glioblastoma
Case Western Reserve University
Nicole Franziska Steinmetz, PhD
Years: 2012-2013
Grant Awarded: $60,000
Generated: $15,941,645
Cancer Type:
Breast Cancer
Project:
A Novel Plant Viral Nanoparticle Drug Delivery System for Treatment of Aggressive HER2+ Breast Cancer
University of Toledo
Jianglong Zhu, PhD
Years: 2012
Grant Awarded: $60,000
Generated: $2,087,892
Cancer Type:
Tumor Studies
Project:
Stereoselective Synthesis of 2-Deoxy-glycosides and Thioglycosides in Antitumor Natural Products
University of Cincinnati
Xiaoting Zhang, PhD
Years: 2011-2012
Grant Awarded: $60,000
Generated: $4,840,809
Cancer Type:
Breast Cancer
Project:
The ER/MED1 Axia and Mammary Stem/Progenitor Cells
The Ohio State University
Victor Jin, PhD
Years: 2011-2012
Grant Awarded: $60,000
Generated: $14,476,599
Cancer Type:
Breast Cancer
Project:
Caharacterization of AKT-mediated Transcriptional Regulation in Breast Cancer
The Ohio State University
Keiko Akagi, PhD
Years: 2011-2012
Grant Awarded: $30,000
Generated: $607,782
Cancer Type:
Leukemia
Project:
Bioinformatics Analysis of Genomic Mutations in Chronic
Nationwide Children's Hospital
Risa Kitagawa, PhD
Years: 2011-2012
Grant Awarded: $60,000
Generated: $1,098,479
Cancer Type:
Tumor Studies
Project:
Securin function in cancer and development
Cincinnati Children's Hospital MC
Gang Huang, PhD
Years: 2011-2012
Grant Awarded: $60,000
Generated: $5,892,237
Cancer Type:
Leukemia
Project:
Molecular mechanisms of leukemogenesis mediated by MLL-partial tandem duplication (MLL-PTD)
Cleveland Clinic Foundation
Tao Lu, PhD
Years: 2010-2011
Grant Awarded: $60,000
Generated: $1,899,715
Cancer Type:
Colon Cancer
Project:
Study the role of FBXL 11 protein in colitis associated cancer (CAC)
Case Western Reserve University
Barbara Bedogni, PhD
Years: 2010-2011
Grant Awarded: $60,000
Generated: $2,496,733
Cancer Type:
Skin Cancer
Project:
Dissecting the role of the Notch signaling pathway in melanoma metastasis
Case Western Reserve University
David Wald, MD, PhD
Years: 2010-2011
Grant Awarded: $60,000
Generated: $7,164,667
Cancer Type:
Leukemia
Project:
Characterization of a novel pathway to selectively target AML cells
Case Western Reserve University
Scott M. Welford, PhD
Years: 2010-2011
Grant Awarded: $60,000
Generated: $4,315,813
Cancer Type:
Radiation, Renal Cancer
Project:
The impact of tissue hypoxia on tumor initiation
Cincinnati Children's Hospital MC
Ruhikantaa Meetei, PhD
Years: 2010-2011
Grant Awarded: $60,000
Generated: $750,000
Cancer Type:
Genetic Research
Project:
Functional and Molecular Characterization of two new members of the Bloom
The Ohio State University
Nina Mayr, MD
Years: 2009-2010
Grant Awarded: $60,000
Generated: $1,536,633
Cancer Type:
Prostate Cancer
Project:
Towards Optimal Radiation Therapy: Radiobiological Modeling of Prostate Cancer
Wright State University
Yong-jie Xu, MD, PhD
Years: 2009-2010
Grant Awarded: $60,000
Generated: $2,060,275
Cancer Type:
Chemotherapy
Project:
Phosphorylation Network of the DNA Replication Checkpoint in Fission Yeast
Cincinnati Children's Hospital MC
Takiko Daikoku, PhD
Years: 2009-2010
Grant Awarded: $60,000
Generated: $5,488,307
Cancer Type:
Endometrial Cancer
Project:
Pten-Akt-Cox2 Signaling Axis in Endometrial Cancer
Ohio University - Athens
Monica Burdick, PhD
Years: 2008-2009
Grant Awarded: $50,000
Generated: $1,089,399
Cancer Type:
Breast Cancer
Project:
Identification of E-selectin Ligands on Breast Cancer Cells
University of Cincinnati
Jinsong Zhang, PhD
Years: 2008-2009
Grant Awarded: $50,000
Generated: $2,298,462
Cancer Type:
Leukemia
Project:
Role of E protein inactivation in leukemogenesis by AML1-ETO
University of Cincinnati
Neville Tam, PhD
Years: 2008-2009
Grant Awarded: $50,000
Generated: $375,623
Cancer Type:
Prostate Cancer
Project:
Dietary Soy and Epigenetic Modulation in Androgen-independent prostate cancer
The Ohio State University
Jian-Qiu Wu, PhD
Years: 2008-2009
Grant Awarded: $25,000
Generated: $2,061,262
Cancer Type:
Molecular Genetics
Project:
Phosphorylation of Anillin Md 1 p bt Polo Kinase During Cytokinesis
University of Dayton
Amit Singh, PhD
Years: 2008-2009
Grant Awarded: $50,000
Generated: $2,242,625
Cancer Type:
Gene Mutation
Project:
A Drosophila model to study the role of the Notch ligand Serrate (Jagged-1) in growth and cancer
University of Toledo
Song-Tao Liu, PhD
Years: 2008-2009
Grant Awarded: $50,000
Generated: $2,621,701
Cancer Type:
Gene Mutation
Project:
Regulation of the Mitotic Checkpoint by hMPS1 Kinase
University of Toledo
Ivana de la Serna, PhD
Years: 2008-2009
Grant Awarded: $50,000
Generated: $1,649,853
Cancer Type:
Skin Cancer
Project:
De-regulation of Chromatin Remodeling by BRAF(V600E) in Melanoma
Case Western Reserve University
Matthias Buck, PhD
Years: 2008-2009
Grant Awarded: $50,000
Generated: $5,683,430
Cancer Type:
Molecular Genetics
Project:
cMet/Eph Phosphorylation of Small GTPases and their Role in Cancer
Case Western Reserve University
Horst Von Recum, PhD
Years: 2008-2009
Grant Awarded: $50,000
Generated: $1,714,636
Cancer Type:
Chemotherapy
Project:
Multiplexing Molecular Interactions to Improve Chemotherapeutic Delivery
Cincinnati Children's Hospital MC
Brian Andrew Gebelein, PhD
Years: 2008-2009
Grant Awarded: $50,000
Generated: $8,477,673
Cancer Type:
Leukemia
Project:
A New Tumor Suppression Pathway in Leukemia
Cincinnati Children's Hospital MC
Anil G. Jegga, DVM
Years: 2008-2009
Grant Awarded: $50,000
Generated: $1,476,237
Cancer Type:
Gene Mutation
Project:
Functional Polymorphisms in p53 Response Elements
University of Cincinnati
Rodney Peter DeKoter, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $1,762,130
Cancer Type:
Leukemia
Project:
A Mouse Model of Myeloid Leukemia Caused By a Novel Hypomorphic Mutation of PU.1
Cleveland Clinic Foundation
Lan Zhou, MD, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $12,346,817
Cancer Type:
Leukemia
Project:
The Role of Aberrant Notch Signaling in the Chronic Myeloproliferative Disorder Induced by Fucosylation Deficiency
Cleveland Clinic Foundation
Malachi Mixon III
Years: 2007-2008
Grant Awarded: $10,000
Generated: TBD
Cancer Type:
Special Gift
Project:
Restricted gift (grant) for cancer research
The Ohio State University
Robert A Baiocchi, MD, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $25,908,099
Cancer Type:
Lymphoma
Project:
Role of the Arginine Methyltansferase PRMT5 in B cell Transformation
The Ohio State University
Rami Aqeilan, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $1,506,126
Cancer Type:
Tumor Cells
Project:
Role of the WW Domain-Containing Oxidoreductase (WWOX) Gene in Skeletal Development and Bone Neoplasia
The Ohio State University
Samir Acharya, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $100,000
Cancer Type:
Colon Cancer
Project:
Role of Mismatch Repair in Cell Survival
The Ohio State University
Harold Fisk, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $2,046,717
Cancer Type:
Molecular Genetics
Project:
Regulation of the Centrosomal Degradation of the Mps1 Protein Kinase
University of Toledo
Steven J. Sucheck, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $6,297,090
Cancer Type:
Tumor Cells
Project:
Solid Phase Synthesis of Cancer Antigenes Containing Decarboxylative Ligation Functionality
University of Toledo
Steven Matthew Patrick, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $3,074,384
Cancer Type:
Gene Mutation
Project:
RPA Phosphorylation and DNA Binding: Roles in the Nbs1/MRN Interaction and ATR Signaling
University of Toledo
Fan Dong, MD, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $2,560,328
Cancer Type:
Gene Mutation
Project:
Gfi-1 in the Regulation of p21 Cip
Case Western Reserve University
Yanwu Yang, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $1,701,735
Cancer Type:
Tumor Research
Project:
Structural Mechanism of How SnoN-FHL2 Complex Activates Wnt/beta-catenin Signaling
Cincinnati Children's Hospital MC
Vrushank G. Dave, PhD
Years: 2007-2008
Grant Awarded: $50,000
Generated: $426,496
Cancer Type:
Lung Cancer
Project:
PTEN/PI3K/AKT Pathway in Lung Cancer
University of Cincinnati
Shan Lu, PhD
Years: 2006-2007
Grant Awarded: $50,000
Generated: $1,363,727
Cancer Type:
Prostate Cancer
Project:
The molecular pathway of Vav3-mediated androgen receptor activation in prostate cancer
University of Cincinnati
Ana Luisa Kadekaro, PhD
Years: 2006-2007
Grant Awarded: $50,000
Generated: $429,788
Cancer Type:
Skin Cancer
Project:
Defining the Regulation of p53 and its Pathway by Autocrine/Paracrine Factors in UVR-irradiated Human Melanocytes
Cleveland Clinic Foundation
Patrick C. Ma, MD
Years: 2006-2007
Grant Awarded: $50,000
Generated: $763,285
Cancer Type:
Lung Cancer
Project:
High-Throughput Cell-Based MET Inhibitor Development For Lung Cancer Individualized Therapy
Case Western Reserve University
Zhilin Hu, PhD
Years: 2006-2007
Grant Awarded: $50,000
Generated: TBD
Cancer Type:
Lung Cancer
Project:
Bronchoscopic OCT imaging to identify premalignant changes in the pulmonary epithelium
Cincinnati Children's Hospital MC
Yi Gu, PhD
Years: 2006-2007
Grant Awarded: $25,000
Generated: $6,098,973
Cancer Type:
Lymphoma
Project:
Role of Rac GTPases in p53-mediated Lymphomagenisis
Cincinnati Children's Hospital MC
James Mulloy, PhD
Years: 2006-2007
Grant Awarded: $25,000
Generated: $9,838,279
Cancer Type:
Leukemia
Project:
Genetic screen for pathways cooperating with AMLl-ETO in leukemia induction
University of Cincinnati
Mario Medvedovic, PhD
Years: 2005-2006
Grant Awarded: $25,000
Generated: $38,791,186
Cancer Type:
Breast Cancer
Project:
Global gene expression profiles for the very early prediction of breast cancer
University of Cincinnati
Craig R. Tomlinson, PhD
Years: 2005-2006
Grant Awarded: $25,000
Generated: $2,912,642
Cancer Type:
Breast Cancer
Project:
Global gene expression profiles for the very early prediction of breast cancer
Cleveland Clinic Foundation
Marie-Odile Parat, PHAR, MD, PhD
Years: 2005-2006
Grant Awarded: $50,000
Generated: $750,000
Cancer Type:
Molecular Genetics
Project:
Role of Caveolin-1 in H-Ras Targeting
The Ohio State University
Xue-Feng Bai, MD, PhD
Years: 2005-2006
Grant Awarded: $50,000
Generated: $5,644,811
Cancer Type:
Gene Mutation
Project:
Novel Strategies to Overcome Antigenic Drift
The Ohio State University
Duxin Sun, PhD
Years: 2005-2006
Grant Awarded: $50,000
Generated: $4,751,266
Cancer Type:
Chemotherapy
Project:
Targeted Prodrug Delivery for Cancer Therapy
The Ohio State University
Susan Cole, PhD
Years: 2005-2006
Grant Awarded: $50,000
Generated: $908,860
Cancer Type:
Molecular Genetics
Project:
Modulation of Lunatic fringe gene activity and Notch signaling in the segmentation clock
The Ohio State University
Laura Ann Kresty, PhD
Years: 2005-2006
Grant Awarded: $50,000
Generated: $3,852,834
Cancer Type:
Esophageal Cancer
Project:
Reversing Epigenetic Changes Through HDAC Inhibition: A Tool for Cancer Prevention
The Ohio State University
Stefan Niewiesk, DVM, PhD
Years: 2005-2006
Grant Awarded: $50,000
Generated: $6,265,102
Cancer Type:
Leukemia
Project:
Induction of oncolysis in Adut T Cell Leukemia Through Heat Shock Protein Induction and Measles Virus Co-Infection
University of Toledo
Douglas Lee Pittman, PhD
Years: 2005-2006
Grant Awarded: $50,000
Generated: $379,816
Cancer Type:
Breast Cancer
Project:
Characterizing the RAD51D E233G High-Risk Breast Cancer Allele
The Ohio State University
Werner Tjarks, PhD
Years: 2003-2004
Grant Awarded: $50,000
Generated: $1,704,411
Cancer Type:
Head and Neck Cancer
Project:
Synthesis of Boron and Gadolinium Containing Texaphyrins For NCT of Head and Neck Cancer
University of Cincinnati
Yolando Sanchez, PhD
Years: 2003-2004
Grant Awarded: $50,000
Generated: TBD
Cancer Type:
Gene Mutation
Project:
The Role of Sfp1 in the Response to DNA Damage
Cincinnati Children's Hospital MC
Susanne Wells, PhD
Years: 2003-2004
Grant Awarded: $50,000
Generated: $12,840,882
Cancer Type:
Cervical Cancer
Project:
DEK Oncogene Regulation by the Human Papillomavirus E6 Proteins
University of Cincinnati
Ying Xia, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $10,589,552
Cancer Type:
Chemotherapy
Project:
Role of MEKK1 in Anticancer Treatment
Cleveland Clinic Foundation
Marina Antoch, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $5,089,663
Cancer Type:
Cancer Therapy
Project:
Diagnostic Markers Of Mammalian Circadian Clock Function
Cleveland Clinic Foundation
Nywana Sizemore, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $1,004,824
Cancer Type:
Breast Cancer
Project:
Molecular Targets Of The PI3K/AKT/IKK Pathway In Breast Cancer
The Ohio State University
Karl Andrew Werbovetz, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $3,990,618
Cancer Type:
Chemotherapy
Project:
Characterization of the Tubulin Peptide Binding Site
The Ohio State University
Denis Guttridge, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $33,924,138
Cancer Type:
Molecular Genetics
Project:
NF-kappa B Regulation of Cell Growth Control in G1/S
University of Toledo
Kam Chi Yeung, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $1,653,992
Cancer Type:
Molecular Genetics
Project:
Substrates of Raf-1 Protein Kinase
Case Western Reserve University
Hung-Ying Kao, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $4,271,228
Cancer Type:
Leukemia
Project:
The Role Of GPS2 In Transcriptional Co-Repressor SMRT-Mediated Repression
Case Western Reserve University
Hua Lou, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $2,641,350
Cancer Type:
Thyroid Cancer
Project:
Medullary Thyroid Carcinoma As A Model To Study Alternative RNA Splicing
Case Western Reserve University
Narendra Narayana, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $121,805
Cancer Type:
Leukemia
Project:
Crystal Structure Determination of DSX-DNA Complex
Metrohealth Medical Center
Subrata Haldar, PhD
Years: 2002-2003
Grant Awarded: $50,000
Generated: $2,814,869
Cancer Type:
Skin Cancer
Project:
Epigenetic Inactivation of Apaf-1 in Metastatic Melanoma
University of Cincinnati
Zalfa A Abdel-Malek, PhD
Years: 2001-2003
Grant Awarded: $50,000
Generated: TBD
Cancer Type:
Skin Cancer
Project:
Oxygen Radicals Mediate the Mutagenic Effects of UVA on Melanocytes
University of Cincinnati
Shiuh-Wen Luoh, MD
Years: 2001-2002
Grant Awarded: $50,000
Generated: TBD
Cancer Type:
Breast Cancer
Project:
HER-2/NEU Amplification In Human Breast Cancer
University of Cincinnati
Andrew Lowy, MD
Years: 2001-2002
Grant Awarded: $50,000
Generated: $9,539,586
Cancer Type:
Stomach Cancer
Project:
Tcf/beta catenin transactivation in gastric cancer
Cleveland Clinic Foundation
Michael Vogelbaum, MD, PhD
Years: 2001-2002
Grant Awarded: $50,000
Generated: $66,300
Cancer Type:
Brain Cancer
Project:
Regulation of Apoptosis in Glioma Primary Cell Cultures
The Ohio State University
Michael B Weinstein, PhD
Years: 2001-2002
Grant Awarded: $50,000
Generated: $1,486,336
Cancer Type:
Molecular Genetics
Project:
Functions of Smad2 in Mesodermal Differentiation and Tumor Progression
University of Toledo
Cynthia M Smas, DSC
Years: 2001-2002
Grant Awarded: $50,000
Generated: $2,476,679
Cancer Type:
Prostate Cancer
Project:
Function of the HLH Protein Id-1 in Prostate Cancer
University of Toledo
Lirim Shemshedini, PhD
Years: 2001-2002
Grant Awarded: $50,000
Generated: $1,862,510
Cancer Type:
Gene Mutation
Project:
Isolation of Repressors of the Androgen Receptor
University of Toledo
Han-Fei Ding, MD, PhD
Years: 2001-2002
Grant Awarded: $50,000
Generated: $6,394,168
Cancer Type:
Genetic Research
Project:
Capase-8 and p53 in N-Myc-Induced Sensitization to Apoptosis
Bowling Green State University
Vladmir V Popik, PhD
Years: 2001-2002
Grant Awarded: $50,000
Generated: $1,238,800
Cancer Type:
Breast Cancer
Project:
Development of Two-Photon Photoactivatable Enediyne Antibiotics
Bowling Green State University
Lakshmidevi Pulakat, PhD
Years: 2001-2002
Grant Awarded: $50,000
Generated: $4,717,107
Cancer Type:
Breast Cancer
Project:
AT2-Mediated Regulation of the ErbB2/3 in Breast Cancer
Cincinnati Children's Hospital MC
Xinhua Lin, PhD
Years: 2001-2002
Grant Awarded: $50,000
Generated: $5,962,307
Cancer Type:
Kidney Cancer
Project:
Role of Dally-like, a Drosophila Glypican in Cell-Cell Signaling
Cincinnati Children's Hospital MC
Susan Waltz, PhD:
Years: 2001-2002
Grant Awarded: $50,000
Generated: $13,199,103
Cancer Type:
Skin Cancer
Project:
Ron in Skin Cancer
Metrohealth Medical Center
Aruna Basu, PhD
Years: 2001-2002
Grant Awarded: $50,000
Generated: $251,000
Cancer Type:
Pancreatic Cancer
Project:
Functional Analysis of LKB1 Gene Linked to Peutz-Jeghers Syndrome
Case Western Reserve University
Nihal Ahmad, PhD
Years: 2001
Grant Awarded: $25,000
Generated: TBD
Cancer Type:
Prostate Cancer, Skin Cancer
Project:
Role of Ornithine Decarboxylase in Phtotcarcinogenesis
Case Western Reserve University
Zhongwu Guo, PhD
Years: 2001
Grant Awarded: $50,000
Generated: $8,628,855
Cancer Type:
Molecular Genetics
Project:
Glycoengineering Cancer Cells for Selective Immunotargeting of Cancer
Ohio University - Athens
Elisar Barbar, PhD
Years: 1999-2000
Grant Awarded: $50,000
Generated: $4,411,728
Cancer Type:
Tumor Research
Project:
Cytoplasmic Dynein: Assembly and Structural Characterization
University of Cincinnati
Jeffrey Sussman, MD
Years: 1999-2000
Grant Awarded: $40,000
Generated: $112,020
Cancer Type:
Skin Cancer
Project:
Immune Response Modulation Improves Cancer Immunotherapy
University of Cincinnati
David S. Askew, PhD
Years: 1999-2000
Grant Awarded: $48,000
Generated: $7,377,147
Cancer Type:
Leukemia
Project:
Function of the His-1 Gene in Leukemogenesis
University of Cincinnati
Arthur Buckley, PhD
Years: 1999-2000
Grant Awarded: $48,000
Generated: $1,223,186
Cancer Type:
Genetic Research
Project:
Novel Tumor Growth, Differentiation, and Apoptosis Genes
University of Cincinnati
Erik Knudsen, PhD
Years: 1999-2000
Grant Awarded: $48,000
Generated: $22,120,631
Cancer Type:
Gene Mutation
Project:
Retinoblastoma Tumor Suppressor: Role in Checkpoint Control
Cleveland Clinic Foundation
Munna Agarwal, PhD
Years: 1999-2000
Grant Awarded: $50,000
Generated: $1,334,067
Cancer Type:
Gene Mutation
Project:
Identification of molecular components involved in regulation of p53 function
The Ohio State University
Pan Zheng, PhD
Years: 1999-2000
Grant Awarded: $50,000
Generated: $12,557,755
Cancer Type:
Prostate Cancer
Project:
Antigen Presentation Defects in Prostate Cancer
The Ohio State University
Sung Yoon, PhD
Years: 1999-2000
Grant Awarded: $46,000
Generated: $14,127,358
Cancer Type:
Molecular Genetics
Project:
Determination of upstream regulators of p75-mediated JNK activation
The Ohio State University
Paivi Peltomaki, MD, PhD
Years: 1999-2000
Grant Awarded: $45,000
Generated: $717,552
Cancer Type:
Colon Cancer
Project:
Genetic basis of tumor spectrum in hereditary nonpolyposis colon cancer
The Ohio State University
Greg Otterson, MD
Years: 1999-2000
Grant Awarded: $46,000
Generated: $2,573,768
Cancer Type:
Lung Cancer
Project:
Molecular Changes in Nonsmall Cell Lung Cancer
The Ohio State University
Louis Mansky, PhD
Years: 1999-2000
Grant Awarded: $46,000
Generated: $16,484,347
Cancer Type:
Leukemia
Project:
Human T-Cell Leukemia Virus Type 1 RNA Encapsidation
The Ohio State University
Tsonwin Hai, PhD
Years: 1999-2000
Grant Awarded: $48,000
Generated: $4,158,346
Cancer Type:
Molecular Genetics
Project:
Caspases in ATF3-Induced Apoptosis
Nationwide Children's Hospital
Joan E Durbin, MD, PhD
Years: 1999-2000
Grant Awarded: $45,000
Generated: $15,503,778
Cancer Type:
Rhabdomyosarcoma
Project:
The Role of the PAX3FKHR Fusion Gene in the Development of Rhabdomyosarcoma
Nationwide Children's Hospital
Natarajan Muthusamy, DVM, PhD
Years: 1999-2000
Grant Awarded: $45,000
Generated: $8,133,688
Cancer Type:
Lymphoma
Project:
Defining thr role of Ets-1 transcription factor in B lymphocyte growth and differentiation
University of Toledo
Gloria Borgstahl, PhD
Years: 1999-2000
Grant Awarded: $50,000
Generated: $3,088,430
Cancer Type:
Genetic Research
Project:
Crystallization of Native and Phosphorylated RPA
University of Cincinnati
Yolando Sanchez, PhD
Years: 1999-2000
Grant Awarded: $48,000
Generated: $13,099,358
Cancer Type:
Gene Mutation
Project:
Identification of novel components of the DNA damage checkpoint pathways
Case Western Reserve University
Nihal Ahmad, PhD
Years: 1999-2000
Grant Awarded: $50,000
Generated: $9,702,157
Cancer Type:
Prostate Cancer, Skin Cancer
Project:
Resveratrol in Prevention of Cancer
Case Western Reserve University
David Danielpour, PhD
Years: 1999-2000
Grant Awarded: $50,000
Generated: $4,908,679
Cancer Type:
Prostate Cancer
Project:
Regulation of TGF-beta signal transduction by IGF-in prostatic cells
Case Western Reserve University
Antonio Gualberto, MD
Years: 1999-2000
Grant Awarded: $50,000
Generated: $49,723
Cancer Type:
Gene Mutation
Project:
Altered Mitotic Checkpoint in p53 mutant cells
Case Western Reserve University
Santosh Katiyar, PhD
Years: 1999-2000
Grant Awarded: $50,000
Generated: $6,061,413
Cancer Type:
Skin Cancer
Project:
UV-induced oxidative stress-mediated human skin cancer, and prevention by antioxidants
Case Western Reserve University
Monica Montano, PhD
Years: 1999-2000
Grant Awarded: $50,000
Generated: $6,750,600
Cancer Type:
Breast Cancer
Project:
Estrogen Receptor-Selective Coactivators in Breast Cancer Cells
University of Cincinnati
Zalfa A. Abdel-Malek, PhD
Years: 1997-1999
Grant Awarded: $40,000
Generated: TBD
Cancer Type:
Skin Cancer
Project:
Elucidation of the Role of the MCI Receptor Gene as a Tumor Susceptibility Gene
University of Cincinnati
Glenn Talaska, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $1,209,567
Cancer Type:
Bladder Cancer
Project:
Benzidine and B-naphitylamine DNA Adducts in Humans
University of Cincinnati
Ranasinghage C. Samaratunga, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $916,264
Cancer Type:
Radiation
Project:
Radiodosimetry for the Treatment of Skeletal Lesions
University of Cincinnati
Michelle Ann Barton, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $39,336,303
Cancer Type:
Breast Cancer
Project:
A cell-free model of p53 nuclear transport dysfuntion in breast cancer cells
University of Cincinnati
Joanne Groden, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $21,436,644
Cancer Type:
Genetic Research
Project:
A Human Helicase and its Effects on Cancer Predisposition and Genomic Instablility
Cleveland Clinic Foundation
Christine Campbell, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $846,843
Cancer Type:
Breast Cancer
Project:
Role of the T-box genes, TBX2 and TBX3, in breast carcinoma
The Ohio State University
Paul Kenneth Herman, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $6,440,651
Cancer Type:
Molecular Genetics
Project:
GO and the control of eukaryotic cell proliferation
The Ohio State University
Sissy M. Jhiang, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $9,800,896
Cancer Type:
Brain Cancer
Project:
Gene Transfer of Na/I Symporter Tumors for Radioiodine Treatment
The Ohio State University
Amanda Simcox, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $4,617,290
Cancer Type:
Molecular Genetics
Project:
Identification of Novel Componets in the Drosophila EGF-Receptor Signaling Pathway
The Ohio State University
Harald Vaessin, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $325,085
Cancer Type:
Molecular Genetics
Project:
Regulation of Cdk inhibitor expression
Wright State University
Steven J. Berberich, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $2,739,347
Cancer Type:
Gene Mutation
Project:
DNA-PK phosphoorylation of the human Mdm-2 oncoprotein
University of Toledo
John David Dignam, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $1,371,815
Cancer Type:
Molecular Genetics
Project:
Adenoassociated Virus Rep78 Protein
Case Western Reserve University
Rajesh Agarwal, PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $26,570,915
Cancer Type:
Prostate Cancer
Project:
Antioxidants and Prostate Cancer Chemoprevention
Cincinnati Children's Hospital MC
Raphael Hirsch, MD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $12,150,923
Cancer Type:
Molecular Genetics
Project:
MHC – Ig Fusion Proteins for Induction pf Tumor Immunity
Metrohealth Medical Center
Bruce Averbook, MD FASC
Years: 1997-1998
Grant Awarded: $40,000
Generated: $3,570,154
Cancer Type:
Brain Cancer
Project:
Brain Tumor Immunosuppression of Tumor Draining Lymph Node Antitumor
The Ohio State University
James William DeWille, MPH MS PhD
Years: 1997-1998
Grant Awarded: $40,000
Generated: $2,397,752
Cancer Type:
Breast Cancer
Project:
Mammary tumors express a C/EBP-b transcritpion inhibitor
University of Cincinnati
Sohaib Khan, PhD
Years: 1995-1997
Grant Awarded: $40,000
Generated: $6,976,584
Cancer Type:
Breast Cancer
Project:
Mechanism of Estrogen Action: Estrogen Receptor Associated Proteins
Cleveland Clinic Foundation
Sipra Banerjee, PhD
Years: 1995-1997
Grant Awarded: $40,000
Generated: $932,400
Cancer Type:
Breast Cancer
Project:
Genomic Instability in Familial Breast Cancer
The Ohio State University
Marshall Vance Williams, PhD
Years: 1995-1997
Grant Awarded: $40,000
Generated: $5,636,586
Cancer Type:
Colon Cancer
Project:
Fluorodeoxyuridine, dUTPASE and Colorectal Cancer
The Ohio State University
Darrell R. Galloway, PhD
Years: 1995-1997
Grant Awarded: $40,000
Generated: $1,023,326
Cancer Type:
Skin Cancer
Project:
Development and Analysis of a Recombinant Protein for the Exogenous Delivery of a Melanoma-specific CTL Peptide
Hipple Cancer Research Center
Sten Eirik Jacobsen, MD, PhD
Years: 1995-1997
Grant Awarded: $40,000
Generated: TBD
Cancer Type:
Leukemia
Project:
TNF Receptors in Normal and Malignant Hematopoiesis
Wright State University
John J. Turchi, PhD
Years: 1995-1997
Grant Awarded: $40,000
Generated: $9,866,884
Cancer Type:
Gene Mutation
Project:
Mechanisms of Mammalian Telomere DNA Replication
Case Western Reserve University
Ellen Rorke, PhD
Years: 1995-1997
Grant Awarded: $40,000
Generated: $1,370,398
Cancer Type:
Cervical Cancer
Project:
Epidermal Growth Factor in Human Cervical Cancer
Cincinnati Children's Hospital MC
Robert Arceci, MD, PhD
Years: 1995-1997
Grant Awarded: $40,000
Generated: $3,823,831
Cancer Type:
Leukemia
Project:
A Preclinical Model for Immunotherapy of AML
Case Western Reserve University
Philip Paul Garner, PhD
Years: 1994-1996
Grant Awarded: $40,000
Generated: $2,072,521
Cancer Type:
Gene Mutation
Project:
The Development of Novel Oligonucleotide Surrogates
Case Western Reserve University
Sanford Markowitz, MD, PhD
Years: 1994-1996
Grant Awarded: $40,000
Generated: $100,178,494
Cancer Type:
Colon Cancer
Project:
Novel Markers of Colon Cancer Progression and Prognosis
University of Toledo
Yian Wang, MD
Years: 1993-1995
Grant Awarded: $40,000
Generated: $3,844,591
Cancer Type:
Liver Cancer
Project:
Study on the Role of H-ras gene in susceptibility of liver tumor in inbred strains of mice.
University of Toledo
Randall Joe Ruch, PhD
Years: 1993-1995
Grant Awarded: $40,000
Generated: $624,819
Cancer Type:
Lung Cancer
Project:
Lung Tumor Growth Inhibition: Role of Gap Junctions
University of Cincinnati
Zalfa A. Abdel-Malek, PhD
Years: 1993-1995
Grant Awarded: $40,000
Generated: $9,038,583
Cancer Type:
Skin Cancer
Project:
Protective Role of Melanin Against Photocarcinogenesis
Case Western Reserve University
Clark W. Distelhorst, MD
Years: 1993-1995
Grant Awarded: $40,000
Generated: $18,354,362
Cancer Type:
Hormone Therapy
Project:
Steroid Receptor Nuclear Uptake Mechanism
The Ohio State University
Michael D Lairmore, DVM, PhD
Years: 1991-1993
Grant Awarded: $40,000
Generated: $22,592,580
Cancer Type:
Lymphoma
Project:
Mechanisms of Regulation of Human T-Lymphotropic Virus
University of Toledo
Ming You, MD, PhD
Years: 1991-1993
Grant Awarded: $40,000
Generated: $58,248,632
Cancer Type:
Lung Cancer
Project:
The Role of Suppressor Genes in the Pathogenesis of Human and Mouse Lung Tumors
University of Toledo
James P. Trempe, PhD
Years: 1991-1993
Grant Awarded: $40,000
Generated: $3,551,030
Cancer Type:
Tumor Cells
Project:
DNA Synthesis Inhibition by a Viral Regulatory Protein
The Ohio State University
Robert Curley, JR, PhD
Years: 1991
Grant Awarded: $20,000
Generated: $5,495,141
Cancer Type:
Chemoprevention
Project:
NMR Studies of Drug-Recepto Ineractions: Chemopreventive Retinoids
The Ohio State University
Arthur L. Sagone, Jr., MD
Years: 1988-1990
Grant Awarded: $40,000
Generated: $95,415
Cancer Type:
Hematology
Project:
Importance of the HMPS Pathway in the Matabolism of Tumor Tissue
The Ohio State University
Brent C. Behrens, MD
Years: 1988-1990
Grant Awarded: $20,000
Generated: TBD
Cancer Type:
Molecular Genetics
Project:
Evaluation of Proton NMR Spectroscopy as and Indicator of Tumor Burden
The Ohio State University
Ing-Ming Chiu, PhD
Years: 1988-1989
Grant Awarded: $40,000
Generated: $3,535,998
Cancer Type:
Leukemia
Project:
Molecular Lesion of 5q- Chromosome in Acute Non-Lymphocytic Leukemia (ANLL) Pateints
Bowling Green State University
Doris J Beck, PhD
Years: 1988-1989
Grant Awarded: $40,000
Generated: $29,840
Cancer Type:
Molecular Genetics
Project:
Repair and Mutagenicity of Damage in DNA caused by Platinum Antitumor Compounds
The Ohio State University
Bruce S. Zwilling, PhD
Years: 1986-1988
Grant Awarded: $40,000
Generated: $7,841,688
Cancer Type:
Gene Mutation
Project:
Cyclic AMP Dependent Protein Kinase, Regulation of Macrophage Antiturmor Activity
The Ohio State University
David H. Ives, PhD
Years: 1986-1988
Grant Awarded: $40,000
Generated: $1,097,284
Cancer Type:
Molecular Genetics
Project:
Development of Solid-Phase Immunoassays for Human Deoxynucleoside Kinase Isoenzymes
Nationwide Children's Hospital
Sue O'Dorisio, MD, PhD
Years: 1986-1988
Grant Awarded: $40,000
Generated: $25,033,799
Cancer Type:
Gastrointestinal
Project:
Vasoactive Intestinal Peptides: Neuromodulator of the Immune Response
Bowling Green State University
William M Scovell, PhD
Years: 1986-1988
Grant Awarded: $40,000
Generated: $764,093
Cancer Type:
Molecular Genetics
Project:
Selective CIS-(NH3)2 PE Cl2 Crosslinking in Chromatin
The Ohio State University
Lee F Johnson, PhD
Years: 1983-1984
Grant Awarded: $48,140
Generated: $2,776,436
Cancer Type:
Thyroid Cancer
Project:
Determination of the Primary Structure of Mammalian Thymidlylate Synthetase
The Ohio State University
Louis Malspeis, PhD
Years: 1983-1984
Grant Awarded: $40,644
Generated: $1,186,774
Cancer Type:
Chemotherapy
Project:
Pharmocologic and Pharmakinetic Studies of Cancer Drugs-Equipment
The Ohio State University
John Rinehart, PhD
Years: 1983-1984
Grant Awarded: $59,376
Generated: $2,269,693
Cancer Type:
Chemotherapy
Project:
Evalution of Biologic Modifiers and Chemotherapeutics
The Ohio State University
James Shaw, PhD
Years: 1983-1984
Grant Awarded: $18,850
Generated: $8,639,993
Cancer Type:
Gene Mutation
Project:
Production of Monoclonal Antibody to EBV-Induced DNA Polymerase
The Ohio State University
Deborah S. Parris, PhD
Years: 1983-1984
Grant Awarded: $43,587
Generated: $5,488,012
Cancer Type:
Molecular Genetics
Project:
Function of Herpes Simplex Virus Deoxribonuclease
The Ohio State University
Robert W Breuggemeier, PhD
Years: 1983
Grant Awarded: $18,850
Generated: $6,261,044
Cancer Type:
Breast Cancer
Project:
Examination of Steroid-Protein Ineractions 12- Using 19f-NMR Spectroscopy
The Ohio State University
Mary Macvicar, RN, PhD
Years: 1982
Grant Awarded: $17,357
Generated: $613,653
Cancer Type:
Breast Cancer
Project:
Effects of Bicycle Ergometer Program in Functional Status of Women with Breast Cancer
The Ohio State University
George E Milo, PhD
Years: 1982
Grant Awarded: $14,796
Generated: $5,204,979
Cancer Type:
Gene Mutation
Project:
Evaluation of Human Tumors by Clonogenic Array
