Brain Cancer

"There are many young scientists in a similar position that could greatly benefit from the support at the early stages in their career."


Justin Lathia, PH.D.
Cleveland Clinic

Molecular Studies

"The Ohio Cancer Research award was instrumental in getting my laboratory off the ground as a new faculty member."


Denis Guttridge, PH.D.
The Ohio State University

Breast Cancer

"For many in my position such achevements would not be possible without these early investments and I thank you for supporting OCR and enabling the cutting edge scientific projects of Ohio's talented young researchers."

Matthew Summers, PH.D.
Cleveland Clinic,
The Ohio State University

Gene Mutation

"The Ohio Cancer Research grant really sowed the seed of success for me to acquire $1.8 million federal funding since I joined the University of Toledo."


Song-Tao Liu, PH.D.
University of Toledo

Lung Cancer

"Research matters because lung cancer is poorly understood and current therapies are insufficient to save the lives of patients."

Anne Strohecker, PH.D.
The Ohio State University

Funded with the support of Celeste and David Loewendick

Breast Cancer

"The lifetime risk of developing invasive breast cancer is 1 in 8 in women in the United States and 20% of the breast cancer patients die. We are exploring strategies to reduce breast cancer deaths in the clinic."


Huiping Liu, M.D., PH.D.
Case Western Reserve University

Cancer Therapy

"Metastasis, the spread of cancer from the original tumor to other sites in the body, is the main cause of death in most cancer patients. We believe our research will contribute to the identification of new therapeutic targets to reduce cancer cell invasion and metastasis."


Jennifer Leight, PH.D.
The Ohio State University

Columbus


The Ohio State University

Funded

Generated

ANNE M STROHECKER, PHD

Regulation of Autophagy by the Small GTPase Rab20

[Lung Cancer]

2015

$60,000

JENNIFER L LEIGHT, PHD

Impact of the tumor microenvironment on matrix metalloproteinase activity

[Cancer Therapy]

2015

$60,000

VICTOR JIN, PHD

Microenvironmental Influences on AKT1-regulated Transcriptome in Tumorigenesis

[Breast Cancer]

2011

$60,000

KEIKO AKAGI, PHD

Bioinformatics Analysis of Genomic Mutations in Chronic Lymphocytic Leukemia

[Leukemia]

2011

$30,000

NINA MAYR, MD

Towards Optimal Radiation Therapy:Radiobiological Modeling of Prostate Cancer

[Prostate Cancer]

2010

$60,000

JIAN-QUI WU, PHD

Phosphorylation of the Anillin Md 1 p bt Polo Kinase During Cytokinesis

[Molecular Genetics]

2008

$25,000

$1,657,958

ROBERT A BAIOCCHI, MD, PHD

Role of the Arginine Methyltansferase PRMT5 in B cell Transformation

[Lymphoma]

2007

$50,000

$908,523

RAMI AQEILAN, PHD

Role of the WW Domain-Containing Oxidoreductase (WWOX) Gene in Skeletal Development and Bone Neoplasia

[Tumor Cells Research]

2007

$50,000

$1,506,126

SAMIR ACHARYA, PHD

Role of Mismatch Repair in Cell Survival

[Colon Cancer]

2007

$24,726

$100,000

HAROLD A FISK, PHD

Regulation of the Centrosomal Degradation of the Mps1 Protein Kinase Melanoma-specific CTL Peptide

[Molecular Genetics]

2007

$50,000

$2,046,717

XUE-FENG BAI, MD, PHD

Novel Strategies to Overcome Antigenic Drift

[Gene Mutation]

2005

$50,000

$981,060

DUXIN SUN, PHD

Targeted Prodrug Delivery for Cancer Therapy

[Chemotherapy]

2005

$50,000

$1,758,726

SUSAN E COLE, PHD

Modulation of Lunatic fringe gene activity and Notch signaling in the segmentation

[Molecular Genetics]

2005

$50,000

$832,277

LAURA ANN KRESTY, PHD

Reversing Epigenetic Changes Through HDAC Inhibition A Tool for Cancer

[Esophageal Cancer]

2005

$49,919

$330,000

STEFAN NIEWIESK, DVM, PHD

Induction of oncolysis in Adut T Cell Leukemia Through Heat Shock Protein Induction and Measles Virus Co-Infection

[Leukemia]

2005

$50,000

$3,203,590

WERNER TJARKS, PHD

Synthesis of Boron and Gadolinium Containing Texaphyrins For NCT of Head and Neck Cancer

[Head and Neck Cancer]

2003

$50,000

$1,305,039

KARL ANDREW WERBOVETZ, PHD

Characterization of the Tubulin Peptide Binding Site

[Chemotherapy]

2002

$50,000

DENIS C GUTTRIDGE, PHD

NF-kappa B Regulation of Cell Growth Control in G1/S

[Molecular Studies]

2002

$50,000

$1,853,191

MICHAEL E WEINSTEIN, PHD

Functions of Smad2 in Mesodermal Differentiation and Tumor Progression

[Molecular Genetics]

2001

$50,000

$20,000

PAN ZHENG, MD

Antigen Presentation Defects in Prostate Cancer

[Prostate Cancer]

1999

$50,000

$778,500

SUNG YOON, PHD

Determination of upstream regulators of p75-mediated JNK activation

[Molecular Genetics]

1999

$46,000

$3,524,081

PAIVI PELTOMAKI, MD, PHD

Genetic basis of tumor spectrum in hereditary nonpolyposis colon cancer

[Colon Cancer]

1999

$45,000

$496,575

GREGORY OTTERSON, MD

Molecular Changes in Nonsmall Cell Lung Cancer

[Lung Cancer]

1999

$46,000

$2,214,946

LOUIS MANSKY, PHD

Human T-Cell Leukemia Virus Type 1 RNA Encapsidation

[Leukemia]

1999

$46,000

$512,568

TSONWIN HAI, PHD

Caspases in ATF3-Induced Apoptosis

[Molecular Genetics]

1999

$48,000

$1,209,505

JAMES WILLIAM DEWILLE, MPH MS PHD

Mammary tumors express a C/EBP-b transcritpion inhibitor

[Breast Cancer]

1997

$39,600

$2,929,435

PAUL KENNETH HERMAN, PHD

GO and the control of eukaryotic cell proliferation

[Molecular Genetics]

1997

$40,000

$3,575,863

SISSY M JHIANG, PHD

Gene Transfer of Na/I Symporter Tumors for Radioiodine Treatment

[Brain Cancer]

1997

$40,000

$2,690,831

AMANDA SIMCOX, PHD

Identification of Novel Componets in the Drosophila EGF-Receptor Signaling

[Molecular Genetics]

1997

$40,000

$306,600

HARALD VAESSIN, PHD

Regulation of Cdk inhibitor expression

[Molecular Genetics]

1997

$38,389

$325,085

MARSHALL VANCE WILLIAMS, PHD

Fluorodeoxyuridine, dUTPASE and Colorectal Cancer

[Colon Cancer]

1995

$38,318

DARRELL R GALLOWAY, PHD

Development and Analysis of a Recombinant Protein for the Melanoma-specific CTL Peptide

[Skin Cancer]

1995

$20,000

MICHAEL D LAIRMORE, DVM, PHD

Mechanisms of Regulation of Human T-Lymphotropic Virus

[Lymphoma]

1991

$39,993

$18,027,125

ROBERT W CURLEY, JR PHD

NMR Studies of Drug-Recepto Ineractions Chemopreventive Retinoids

[Chemoprevention]

1991

$20,000

$129,000

ING-MING CHIU, PHD

Molecular Lesion of 5q- Chromosome in Acute Non-Lymphocytic Leukemia (ANLL) Patients

[Leukemia]

1988

$39,000

$6,988,789

ARTHUR L SAGONE, JR MD

Importance of the HMPS Pathway in the Matabolism of Tumor Tissue

[Hematology]

1988

$35,100

BRENT C BEHRENS, MD

Evaluation of Proton NMR Spectroscopy as an Indicator of Tumor Burden

[Molecular Genetics]

1988

$15,762

BRUCE S ZWILLING, PHD

Cyclic AMP Dependent Protein Kinase, Regulation of Macrophage Antiturmor

[Gene Mutation]

1986

$35,557

DAVID H IVES, PHD

Development of Solid-Phase Immunoassays for Human Deoxynucleoside Kinase Isoenzymes

[Molecular Genetics]

1986

$34,348

$614,514

ROBERT W BRUEGGEMEIER, PHD

Examination of Steroid-Protein Ineractions 12 Using 19f-NMR Spectroscopy

[Breast Cancer]

1983

$18,850

$4,491,883

LEE F JOHNSON, PHD

Determination of the Primary Structure of Mammalian Thymidlylate Synthetase

[Thyroid Cancer]

1983

$48,140

$2,776,436

LOUIS MALSPEIS, PHD

Pharmocologic and Pharmakinetic Studies of Cancer Drugs-Equipment

[Chemotherapy Delivery]

1983

$40,644

JOHN RINEHART, PHD

Evalution of Biologic Modifiers and Chemotherapeutics

[Chemotherapy]

1983

$59,376

JAMES SHAW, PHD

Production of Monoclonal Antibody To EBV-Induced DNA Polymerase

[Gene Mutation]

1983

$18,850

DEBORAH S PARRIS, PHD

Function of Herpes Simplex Virus Deoxribonuclease

[Molecular Genetics]

1983

$43,587

$4,006,291

MARY MACVICAR, RN, PHD

Effects of Bicycle Ergometer Program in Functional Status of Women with Breast Cancer

[Breast Cancer]

1982

$17,357

$497,307

GEORGE E MILO, PHD

Evaluation of Human Tumors by Clonogenic Array

[Gene Mutation]

1982

$14,796

TOTAL:

$1,938,312

$72,598,541

Nationwide Children's Hospital

Funded

Generated

RISA KITAGAWA, PHD

Securin function in cancer and development

[Tumor Studies]

2011

$30,000

JOAN DURBIN, MD, PHD

The Role of the PAX3FKHR Fusion Gene in the Development of Rhabdomyosarcoma

[Rhabdomyosarcoma]

1999

$45,000

$1,431,149

NATARAJAN MUTHUSAMY, DVM, PHD

Defining thr role of Ets-1 transcription factor in B lymphocyte growth and didderentiation

[Lymphoma]

1999

$45,000

$919,800

SUE O'DORISIO, MD, PHD

Vasoactive Intestinal Peptides: Neuromodulator of the Immune Response

[Gastrointestinal]

1986

$39,986

$910,452

TOTAL:

$159,986

$3,261,401