Brain Cancer

"There are many young scientists in a similar position that could greatly benefit from the support at the early stages in their career."


Justin Lathia, PH.D.
Cleveland Clinic

Molecular Studies

"The Ohio Cancer Research award was instrumental in getting my laboratory off the ground as a new faculty member."


Denis Guttridge, PH.D.
The Ohio State University

Breast Cancer

"For many in my position such achevements would not be possible without these early investments and I thank you for supporting OCR and enabling the cutting edge scientific projects of Ohio's talented young researchers."

Matthew Summers, PH.D.
Cleveland Clinic,
The Ohio State University

Gene Mutation

"The Ohio Cancer Research grant really sowed the seed of success for me to acquire $1.8 million federal funding since I joined the University of Toledo."


Song-Tao Liu, PH.D.
University of Toledo

Lung Cancer

"Research matters because lung cancer is poorly understood and current therapies are insufficient to save the lives of patients."

Anne Strohecker, PH.D.
The Ohio State University

Funded with the support of Celeste and David Loewendick

Breast Cancer

"The lifetime risk of developing invasive breast cancer is 1 in 8 in women in the United States and 20% of the breast cancer patients die. We are exploring strategies to reduce breast cancer deaths in the clinic."


Huiping Liu, M.D., PH.D.
Case Western Reserve University

Cancer Therapy

"Metastasis, the spread of cancer from the original tumor to other sites in the body, is the main cause of death in most cancer patients. We believe our research will contribute to the identification of new therapeutic targets to reduce cancer cell invasion and metastasis."


Jennifer Leight, PH.D.
The Ohio State University

Cincinnati


University of Cincinnati

Funded

Generated

XIAOTING ZHANG, PHD

The ER/MED1 Axis and Mammary Stem/Progenitor Cells

[Breast Cancer]

2011

$60,000

$1,807,125

JINSONG ZHANG, PHD

Role of E Protein Inactivation in Leukemogenesis by AML1-ETO

[Leukemia]

2008

$35,000

$1,935,998

NEVILLE TAM, PHD

Dietary Soy and Epigenetic Modulation in Androgen-independent Prostrate Cancer

[Prostate Cancer]

2008

$49,857

$375,623

RODNEY PETER DEKOTER, PHD

A Mouse Model of Myeloid Leukemia Caused By a Novel Hypomorphic Mutation of PU.1

[Leukemia]

2007

$50,000

$1,762,130

SHAN LU, PHD

The molecular pathway of Vav3-mediated androgen receptor activation in prostate cancer

[Prostate Cancer]

2006

$50,000

$1,325,359

ANA LUISA KADEKARO, PHD

Defining the Regulation of p53 and its Pathway by Autocrine/Paracrine Factors in UVR-irradiated Human Melanocytes

[Skin Cancer]

2006

$49,998

$429,788

MARIO MEDVEDOVIC, PHD

Global gene expression profiles for the very early prediction of breast cancer

[Breast Cancer]

2005

$25,000

CRAIG R TOMLINSON, PHD

Global gene expression profiles for the very early prediction of breast cancer

[Breast Cancer]

2005

$25,000

YOLANDA SANCHEZ, PHD

The Role of Sfp1 in the Response to DNA Damage

[Gene Mutation]

2004

$50,000

YING XIA, PHD

Role of MEKK1 in Anticancer Treatment

[Chemotherapy]

2002

$50,000

$5,067,800

ZALFA A ABDEL-MALEK, PHD

Oxygen Radicals Mediate the Mutagenic Effects of UVA on Melanocytes

[Skin Cancer]

2001

$16,716

$4,128,744

SHIUH WEN LUOH, MD

HER-2/NEU Amplification In Human Breast Cancer

[Breast Cancer]

2001

$50,000

ANDREW M LOWY, MD

Tcf/beta catenin transactivation in gastric cancer

[Stomach Cancer]

2001

$49,690

$2,480,638

JEFFREY J SUSSMAN, MD

Immune Response Modulation Improves Cancer Immunotherapy

[Skin Cancer]

1999

$24,335

$112,020

YOLANDA SANCHEZ, PHD

Identification of novel components of the DNA damage checkpoint pathways

[Gene Mutation]

1999

$50,000

$7,794,074

DAVID ASKEW, PHD

Function of the His-1 Gene in Leukemogenesis

[Leukemia]

1999

$24,000

ARTHUR BUCKLEY, PHD

Novel Tumor Growth, Differentiation, and Apoptosis Genes

[Genetic Research]

1999

$48,000

ERIK KNUDSEN, PHD

Retinoblastoma Tumor Suppressor: Role in Checkpoint Control

[Gene Mutation]

1999

$48,000

$1,430,446

GLENN TALASKA, PHD

Benzidine and B-naphitylamine DNA Adducts in Humans

[Bladder Cancer]

1997

$40,000

$690,180

RANASINGHAGE C SAMARATUNGA, PHD

Radiodosimetry for the Treatment of Skeletal Lesions

[Radiation]

1997

$19,806

MICHELLE CRAIG BARTON, PHD

A cell-free model of p53 nuclear transport dysfuntion in breast cancer cells

[Breast Cancer]

1997

$40,000

ZALFA A ABDEL-MALEK, PHD

Elucidation of the Role of the MCI Receptor Gene as a Tumor Susceptibility Gene

[Skin Cancer]

1997

$20,000

$1,236,364

JOANNA GRODEN, PHD

A Human Helicase and its Effects on Cancer Predisposition and Genomic Instablility

[Genetic Research]

1997

$40,000

$11,596,062

SOHAIB A KHAN, PHD

Mechanism of Estrogen Action: Estrogen Receptor Associated Proteins

[Breast Cancer]

1995

$40,000

$2,364,454

ZALFA A ABDEL-MALEK, PHD

Protective Role of Melanin Against Photocarcinogenesis

[Skin Cancer]

1993

$39,996

$1,633,312

TOTAL:

$995,398

$46,170,117

Cincinnati Children's Hospital Medical Center

Funded

Generated

SAULIUS SUMANAS, PHD

Inhibition of Etv2 function as a novel strateg to prevent tumor-induced

[Tumor Studies]

2013

$60,000

$50,000

GANG HUANG, PHD

Molecular mechanisms of leukemogenesis mediated by MLL-partial tandem duplication (MLL-PTD)

[Leukemia]

2011

$60,000

$871,650

RUHIKANTA MEETEI, PHD

Functional and Molecular Characterization of two new members of the Bloom

[Genetic Research]

2010

$60,000

TAKIKO DAIKOKU, PHD

Pten-Akt-Cox2 Signaling Axis in Endometrial Cancer

[Endometrial Cancer]

2010

$60,000

$5,488,307

ANIL G JEGGA, DVM

Functional Polymorphisms in p53 Response Elements

[Gene Mutation]

2008

$50,000

BRIAN ANDREW GEBELEIN, PHD

A New Tumor Suppression Pathway in Leukemia

[Leukemia]

2008

$50,000

VRUSHANK G DAVE, PHD

PTEN/PI3K/AKT Pathway in Lung Cancer

[Lung Cancer]

2007

$50,000

$308,000

JAMES MULLOY, PHD

Genetic screen for pathways cooperating with AMLl-ETO in leukemia induction

[Leukemia]

2006

$50,000

$1,066,794

YI GU, PHD

Role of Rac GTPases in p53-mediated Lymphomagenisis

[Lymphoma]

2006

$25,000

SUSANNE WELLS, PHD

DEK Oncogene Regulation by the Human Papillomavirus E6 Proteins

[Cervical Cancer]

2003

$50,000

$2,864,905

SUSAN WALTZ, PHD

Ron in Skin Cancer

[Skin Cancer]

2001

$50,000

$1,658,546

XINHUA LIN, PHD

Role of Dally-like, a Drosophila Glypican in Cell-Cell Signaling

[Kidney Cancer]

2001

$50,000

$3,587,797

RAPHAEL HIRSCH, MD

MHC - Ig Fusion Proteins for Induction pf Tumor Immunity

[Molecular Genetics]

1997

$40,000

$1,757,955

ROBERT ARCECI, MD, PHD

A Preclinical Model for Immunotherapy of AML

[Leukemia]

1995

$40,000

$1,352,196

TOTAL:

$695,000

$19,006,150